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ID 34995
file
creator
Kenjo, Masahiro
Kobatake, Kohei
Iwamoto, Hideo
Goriki, Akihiro
Oki, Mami
Shoji, Koichi
Miyamoto, Katsutoshi
Masumoto, Hiroshi
Kobayashi, Kanao
Ohara, Shinya
Murakami, Yuji
Kaneyasu, Yuko
subject
Brachytherapy
Localized prostate cancer
Iodine-125 seed
NDC
Medical sciences
abstract
This report presents the outcome of prostate permanent brachytherapy (PPB). One hundred and seventy-two patients with clinically localized prostate cancer were treated with permanent brachytherapy using iodine-125 seeds (125-I) at Hiroshima University Hospital from July 2004 to June 2010. This study evaluated the efficacy of PPB in these patients. The median patient age was 69 years (range 53 to 82 years), the median prostate-specific antigen (PSA) value before biopsy was 6.75 ng/ml (range 3.5 to 47.9 ng/ml), and the median prostate volume was 23.1 ml (range 10.1 to 57 ml). The median follow-up was 37 months (range 1 to 72 months). The serum PSA levels decreased continuously after PPB throughout the entire follow-up period in 97% of patients without neoadjuvant hormonal therapy. No relapse occurred during the follow-up period in patients at low risk. Our 6-year experience suggests that PPB is effective for localized prostate cancer. Patients with prostate cancer that does not require combined External beam radiation therapy (EBRT) have the best chance of responding to treatment.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 60
issue
Issue 3
start page
51
end page
56
date of issued
2011-09
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
rights
(c) Hiroshima University Medical Press.
department
Graduate School of Biomedical Science
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