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ID 17082
file
creator
Nishikubo, Shuichi
Ikura, Masae
Fujiwara, Tamaki
Komatsuzawa, Hitoshi
NDC
Medical sciences
abstract
Clinical Actinobacillus actinomycetemcomitans produces cytolethal distending toxin (CDT) with titers varying from 102 to 108 U/mg. SNP analysis of the Cdt gene in clinical isolates identified a variation of single amino acid at residue 281 of CdtB, which significantly affected CDT toxicity by modulating chromatin degrading activity of CdtB.
journal title
Infection and Immunity
volume
Volume 74
issue
Issue 12
start page
7014
end page
7020
date of issued
2006-12
publisher
American Society for Microbiology
issn
0019-9567
ncid
publisher doi
pubmed id
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
Copyright (c) 2006 American Society for Microbiology.
relation is version of URL
http://dx.doi.org/10.1128/IAI.02063-05
department
Graduate School of Biomedical Science