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ID 37711
file
creator
Marubayashi, Seiji
Watanabe, Hiroshi
Fudaba, Yasuhiro
Hayamizu, Keisuke
Okimasa, Seiji
Katayama, Kohji
Itamoto, Toshiyuki
Haruta, Naoki
Okajima, Masazumi
Sugino, Keizou
Yahata, Hiroshi
Ishikawa, Tetsuo
Fukuda, Yasuhiko
Dohi, Kiyohiko
Asahara, Toshimasa
subject
Malignant Tumor
Renal Transplantation
NDC
Medical sciences
abstract
The high incidence of cancer after renal transplantation is now a critical concern since the graft survival rate has been improved extensively. We experienced 9 malignancies in 8 patients out of 168 recipients up to December 31, 1999 in our hospital, consisting of a case of gastric plasmacytoma and cases of cancer in the liver (2), thyroid (2), prostate (1), breast (1), sigmoid colon (1) and gall-bladder (1). Two patients were diagnosed as having tumors within 3 months after transplantation, suggesting post-transplant acceleration of growth of the latent tumors. The other patients were diagnosed at an average of 128 months, ranging from 84 to 263 months after transplant. Two patients died of gastro-intestinal bleeding and acute heart failure. Four patients died directly of progressive neoplasm within 3 months after diagnosis. These results suggest that the course of malignancies developing in post-transplant recipients is more aggressive than that expected in non-transplant patients, and it is very important to intensively follow long-term surviving cases to detect the malignant tumors as early as possible.
journal title
Hiroshima Journal of Medical Sciences
volume
Volume 49
issue
Issue 2
start page
117
end page
120
date of issued
2000-06
publisher
Hiroshima University Medical Press
issn
0018-2052
ncid
language
eng
nii type
Departmental Bulletin Paper
HU type
Departmental Bulletin Papers
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical Science
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