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ID 47564
file
title alternative
Three Cases Becoming Difficult to Remove Epidural Catheter Postoperatively Due to Coagulation Defect Associated with Antibiotics
creator
Hirata, Yuri
Masuda, Yoko
subject
ビタミンK欠乏症
硬膜外麻酔
抗生剤
NMTT 基
PIVKA-II
vitamin K deficiency
epidural anesthesia
antibiotic
N-methyltetrazolethiol
NDC
Medical sciences
abstract
Perioperative vitamin K deficiency can cause severe coagulopathy rapidly. Vitamin K deficiency tends to be overlooked despite the elucidation of pathophysiology and countermeasures. The main causes of vitamin K deficiency are insufficient intake, low supply from intestinal bacteria, and synthesis inhibition of vitamin K by N-methyltetrazolethiol (N - MTT) contained antibiotics. We experienced three cases in which it was difficult to remove epidural catheter because of coagulation abnormality due to vitamin K deficiency after surgery. Vitamin K deficiency should be wary of when epidural catheter is indwelled or withdrawn from a patient who is administered with antibiotic containing N-MTT in the fasted state.
journal title
Ansesthesia and Resuscitation
volume
Volume 55
issue
Issue 1
start page
45
end page
47
date of issued
2019-03-01
publisher
広島麻酔医学会
issn
0385-1664
ncid
language
jpn
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
publisher
department
Graduate School of Biomedical & Health Sciences
University Medical Hospital
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