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ID 34813
file
creator
Fukumori, Rika
Shingu, Hiroyuki
Moriya, Naoko
Hasegawa, Yoshihisa
Kojima, Masayasu
Kangawa, Kenji
Kushibiki, Shiro
Taniguchi, Kouzo
subject
Dairy cow
Fatty acid
Ghrelin
Glucagon-like peptide-1 (7 to 36) amide
Methionine
NDC
Animal husbandry
abstract
Our objective was to determine the effects of calcium salts of long-chain fatty acids (CLFAs) and rumen-protected methionine (RPM) on plasma concentrations of ghrelin, glucagon-like peptide-1 (7 to 36) amide, and pancreatic hormones in lactating cows. Four Holstein cows in midlactation were used in a 4 by 4 Latin square experiment in each 2-wk period. Cows were fed corn silage-based diets with supplements of CLFAs (1.5% added on dry matter basis), RPM (20 g/d), CLFAs plus RPM, and without supplement. Jugular blood samples were taken from 1 h before to 2 h after morning feeding at 10-min intervals on day 12 of each period. CLFAs decreased dry matter intake, but RPM did not affect dry matter intake. Both supplements of CLFAs and RPM did not affect metabolizable energy intake and milk yield and composition. Plasma concentrations of NEFAs, triglyceride (TG), and total cholesterol (T-Cho) were increased with CLFAs alone, but increases of plasma concentrations of TO and T-Cho were moderated by CLFAs plus RPM. Calcium salts of long-chain fatty acids increased plasma ghrelin concentration, and the ghrelin concentration with CLFAs plus RPM was the highest among the treatments. Plasma concentrations of glucagon-like peptide-1, glucagon, and insulin were decreased with CLFAs, whereas adding RPM moderated the decrease of plasma glucagon concentration by CLFAs. These results indicate that the addition of methionine to cows given CLFAs increases plasma concentrations of ghrelin and glucagon associated with the decrease in plasma concentrations of TO and T-Cho.
journal title
Domestic Animal Endocrinology
volume
Volume 42
issue
Issue 2
start page
74
end page
82
date of issued
2012
publisher
Elsevier Science INC
issn
0739-7240
ncid
publisher doi
language
eng
nii type
Journal Article
HU type
Journal Articles
DCMI type
text
format
application/pdf
text version
author
rights
(c) 2012 Elsevier Inc. All rights reserved.
relation url
department
Graduate School of Biosphere Science



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