Elevation of Collagenase Activity in Fatty Liver

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Title ( eng )
Elevation of Collagenase Activity in Fatty Liver
Creator
WATANABE Akiharu
KOBAYASHI Michio
Source Title
Hiroshima Journal of Medical Sciences
Volume 36
Issue 4
Start Page 417
End Page 419
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Liver collagenase activity increased without liver cell necrosis in non-alcoholic and alcoholic fatty liver induced by feeding rats a choline-deficient diet or alcohol-liquid diet, respectively. The liver hydroxyproline content did not increase during a marked rise in collagenase activity in non-alcoholic fatty liver, but the content gradually increased after collagenase activity diminished. However, the hydroxyproline content increased slowly with a slight concomitant increase in collagenase activity in alcoholic fatty liver. The regulatory mechanism of fibrogenesis in fatty liver is discussed.
Keywords
Collagenase
Collagen
Fatty Liver
Liver fibrosis
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 1987-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2834308