Bile Acid and Ammonia-Induced Brain Edema in Rats
Hiroshima Journal of Medical Sciences Volume 36 Issue 2
Page 257-259
published_at 1987-06
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| File | |
| Title ( eng ) |
Bile Acid and Ammonia-Induced Brain Edema in Rats
|
| Creator |
WATANABE Akiharu
FUJIWARA Masachika
TOMINAGA Satoru
NAGASHIMA Hideo
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 36 |
| Issue | 2 |
| Start Page | 257 |
| End Page | 259 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
Infusion of bile acid such as chenodeoxycholic acid or deoxycholic acid through the carotid artery of rats produced reversible and unilateral opening of the blood-brain barrier without any tissue damage. Intravenous drip infusion of ammonium acetate during the opening resulted in severe edema of the brain. The results suggest the importance of bile acid and ammonia for the pathogenesis of brain edema frequently observed in acute hepatic failure.
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| Keywords |
Brain edema
Bile acid
Ammonia
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima Journal Medical Press
|
| Date of Issued | 1987-06 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3654274
|
