Endocrine Profile in Rats with Postgastrectomy Malabsorption: a Pilot Study

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タイトル ( eng )
Endocrine Profile in Rats with Postgastrectomy Malabsorption: a Pilot Study
作成者
KISHIMOTO Shinya
KONEMORI Reiko
KAMBARA Akihiko
OKAMOTO Kazuma
SHIMIZU Satoru
KOH Hassei
KUNITA Toshiro
DAITOKU Kunihiko
KAJIYAMA Goro
収録物名
Hiroshima Journal of Medical Sciences
34
2
開始ページ 209
終了ページ 213
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
Abnormal endocrine profile, especially in the enteropancreatic axis, was described in rats with malnutrition caused by malabsorption after total gastrectomy. Insulin, substance P and motilin concentrations at the fasting condition were significantly elevated in malnutritious rats after total gastrectomy when compared to those in control rats. A significant elevation of pancreatic glucagon and motilin was noted after intraduodenal fat administration in malnutritious rats. These data suggest that these peptides of many humoral factors may thus cause abnormal enteropancreatic axis and consequent malnutrition.
著者キーワード
Postgastrectomy
Insulin
Pancreatic glucagon
Motilin
Substance P
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1985-06
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 2411681