Experimental Study on Orientation of Regenerating Fibers in the Severed Peripheral Nerve
Hiroshima Journal of Medical Sciences Volume 32 Issue 4
Page 389-406
published_at 1983-12
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| File | |
| Title ( eng ) |
Experimental Study on Orientation of Regenerating Fibers in the Severed Peripheral Nerve
|
| Title ( jpn ) |
末梢神経損傷における再生線維の方向性に関する実験的研究
|
| Creator | |
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 32 |
| Issue | 4 |
| Start Page | 389 |
| End Page | 406 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
The objective of this study was to ascertain how the orientation of regenerating fibers of the proximal stump of severed peripheral nerves is determined at time of growth. In other words, a gap was intentionally created between the both stumps of severed peripheral nerves to determine whether regenerating fibers are guided in the direction of the distal stump or if they grow randomly. The following results were obtained.
1) Regenerating fibers sprouting from the proximal stump definitely extend in the direction of the distal stump. 2) Even when the distal stump is replaced with a nerve fragment, the regenerating fibers grow in that direction. These results are completely different from those of Weiss and Taylor, and thus the conclusion was reached that the possibility the orientation of regenerating fibers is determined by chemotaxis cannot be ruled out. |
| Keywords |
Regenerating nerve fibers
Orientation
Chemotaxis
Contact guidance
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1983-12 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6678898
|
