Experimental Study on Orientation of Regenerating Fibers in the Severed Peripheral Nerve

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タイトル ( eng )
Experimental Study on Orientation of Regenerating Fibers in the Severed Peripheral Nerve
タイトル ( jpn )
末梢神経損傷における再生線維の方向性に関する実験的研究
作成者
収録物名
Hiroshima Journal of Medical Sciences
32
4
開始ページ 389
終了ページ 406
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
The objective of this study was to ascertain how the orientation of regenerating fibers of the proximal stump of severed peripheral nerves is determined at time of growth. In other words, a gap was intentionally created between the both stumps of severed peripheral nerves to determine whether regenerating fibers are guided in the direction of the distal stump or if they grow randomly. The following results were obtained.

1) Regenerating fibers sprouting from the proximal stump definitely extend in the direction of the distal stump.

2) Even when the distal stump is replaced with a nerve fragment, the regenerating fibers grow in that direction.

These results are completely different from those of Weiss and Taylor, and thus the conclusion was reached that the possibility the orientation of regenerating fibers is determined by chemotaxis cannot be ruled out.
著者キーワード
Regenerating nerve fibers
Orientation
Chemotaxis
Contact guidance
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University School of Medicine
発行日 1983-12
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6678898