Chromosome Analysis of Bone Marrow Fibroblast Colony-Forming Cells (CFU-F) in Heavily Exposed Atomic Bomb Survivors

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Title ( eng )
Chromosome Analysis of Bone Marrow Fibroblast Colony-Forming Cells (CFU-F) in Heavily Exposed Atomic Bomb Survivors
Title ( jpn )
近距離原爆被爆者における骨髄線維芽細胞(CFU-F)の染色体分析
Creator
Shigeta Chiharu
Tanaka Kimio
Kawakami Masahito
Ohkita Takeshi
Source Title
Hiroshima Journal of Medical Sciences
Volume 33
Issue 4
Start Page 659
End Page 662
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
A chromosome analysis was performed on cultured bone marrow fibroblasts (CFU-F) from two atomic bomb survivors exposed within 1 km of the hypocenter, whose estimated radiation dose is 357 rad and 365 rad respectively. In CFU-F of both cases, stable types of chromosome aberrations were detected. The rate of these chromosome aberrations related well to the chromosome aberration rate of peripheral T -lymphocytes of the same case. These findings suggest the possibility that chromosome aberration exists in somatic cells other than hematopoietic cells of heavily exposed atomic bomb survivors.
Keywords
Chromosome aberration
Atomic bomb survivor
Fibroblast
CFU-F
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1984-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6534923