Relationships Among Blood Leptin and Adiponectin Levels, Fat Mass, and Bone Mineral Density in Japanese Pre- and Postmenopausal Women

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タイトル ( eng )
Relationships Among Blood Leptin and Adiponectin Levels, Fat Mass, and Bone Mineral Density in Japanese Pre- and Postmenopausal Women
作成者
Iida Tadayuki
Domoto Tokio
Takigawa Atsushi
Nakamura Satoru
Kato Yoji
Togo Masanori
Chikamura Chiho
Harada Toshihide
Ishizaki Fumiko
Ono Yuichiro
収録物名
Hiroshima Journal of Medical Sciences
60
4
開始ページ 71
終了ページ 78
収録物識別子
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
抄録
We conducted a survey of 111 healthy middle-aged and older women, aged 40 to 80 years, to elucidate the relationships between blood leptin and adiponectin levels and bone mineral density (BMD) in September 2008. We examined the associations between the blood levels of these adipocytokines and the lumbar spine (L2-L4), left femoral, and distal forearm BMD after adjustment for the age and body fat percentage. No correlation was observed between leptin and the BMD. This is presumably due to the fact that the influence of menopause, age, duration of postmenopausal period, and body fat percentage on the BMD is greater than that of leptin levels in healthy women. The adiponectin levels were significantly correlated negatively with the lumbar spine and femoral BMD in premenopausal women, and with forearm BMD in postmenopausal women, regardless of adjustment for age and body fat percentage. It seems likely that adiponectin influences the BMD at different skeletal sites in pre- and postmenopausal women.
著者キーワード
Leptin
Adiponectin
BMD
Women
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 紀要論文
出版者
Hiroshima University Medical Press
発行日 2011-12
権利情報
(c) Hiroshima University Medical Press.
出版タイプ Version of Record(出版社版。早期公開を含む)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 0018-2052
[NCID] AA00664312