Activation of fast sleep spindles at the premotor cortex and parietal areas contributes to motor learning: A study using sloreta

Clinical Neurophysiology 120 巻 5 号 878-886 頁 2009 発行
アクセス数 : 768
ダウンロード数 : 253

今月のアクセス数 : 4
今月のダウンロード数 : 5
ファイル情報(添付)
ClinNeur_120_878.pdf 425 KB 種類 : 全文
タイトル ( eng )
Activation of fast sleep spindles at the premotor cortex and parietal areas contributes to motor learning: A study using sloreta
作成者
Tamaki Masako
Matsuoka Tatsuya
Hori Tadao
収録物名
Clinical Neurophysiology
120
5
開始ページ 878
終了ページ 886
抄録
Objective: The present study examined whether slow and/or fast sleep spindles are related to visuomotor learning, by examining the densities of current sleep spindle activities. Methods: Participants completed a visuomotor task before and after sleep on the learning night. This task was not performed on the non-learning night. Standard polysomnographic recordings were made. After the amplitudes of slow and fast spindles were calculated, sLORETA was used to localize the source of slow and fast spindles and to investigate the relationship between spindle activity and motor learning. Results: Fast spindle amplitude was significantly larger on the learning than on the non-learning nights, particularly at the left frontal area. sLORETA revealed that fast spindle activities in the left frontal and left parietal areas were enhanced when a new visuomotor skill was learned. There were no significant learning-dependent changes in slow spindle activity. Conclusions: Fast spindle activity increases in cortical areas that are involved in learning a new visuomotor skill. The thalamocortical network that underlies the generation of fast spindles may contribute to the synaptic plasticity that occurs during sleep. Significance: Activity of fast sleep spindles is a possible biomarker of memory deficits.
著者キーワード
Sleep
Memory
Learning
Sleep spindle
Fast spindle
Premotor cortex
Parietal associative area
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 学術雑誌論文
出版者
Elsevier Ireland Ltd
発行日 2009
権利情報
Copyright (c) 2009 International Federation of Clinical Neurophysiology Published by Elsevier Ireland Ltd.
出版タイプ Author’s Original(十分な品質であるとして、著者から正式な査読に提出される版)
アクセス権 オープンアクセス
収録物識別子
[ISSN] 1388-2457
[DOI] 10.1016/j.clinph.2009.03.006
[NCID] AA11309888
[DOI] http://dx.doi.org/10.1016/j.clinph.2009.03.006